Is Creatine Safe? A Science-Backed Look at the World's Most Studied Supplement
- Clean Supplements
- Jul 19
- 3 min read
Updated: 6 days ago

Before you add any new supplement to your routine, it’s smart to ask the most important question: “Is it safe?”
When it comes to creatine, the internet is full of conflicting information. It can be difficult to know what to believe. Doing your own research is the first step toward making a confident and informed decision for your health.
We will look at what decades of scientific research suggest about creatine, and specifically, creatine monohydrate. We’ll examine the common myths and present the evidence-based information, allowing you to better understand this popular supplement.
What Is Creatine, Really? (Hint: It’s Not a Steroid)
Let’s start by clearing up a major misconception. Creatine is not a steroid or a foreign synthetic chemical.
It’s a natural compound that your body already produces from amino acids. You have creatine in your system right now, and you also get it from common foods like red meat and fish.
Think of creatine’s role in the body as supporting your natural energy cycle. It plays a key part in recycling the body's main energy molecule, ATP (adenosine triphosphate). When your muscle or brain cells use energy, creatine is involved in the process of replenishing that ATP. Supplementing with creatine simply provides additional support for this natural cellular process.
Debunking a Common Myth: Creatine and Kidney Health
One of the most persistent rumors about creatine is that it may negatively affect the kidneys. This concern is so widespread that it deserves a direct look.
Here’s the truth: Major scientific bodies have reviewed the extensive body of research and have concluded that for healthy individuals, creatine supplementation does not negatively affect kidney function.
The confusion often stems from a misunderstanding of how kidney health is measured.
When your body uses creatine, it produces a waste product called creatinine.
Doctors often measure blood creatinine levels as a marker for kidney function.
Taking creatine supplements can slightly elevate blood creatinine levels.
This confusion between creatine and creatinine is the single biggest reason for the myth's persistence.
To help clarify this point, Dr. Andy Galpin, a leading expert in muscle physiology, explains it simply in this short video:
As Dr. Galpin points out, this expected rise in creatinine is a normal physiological response for a creatine user and not an indication of kidney damage. Understanding this key distinction is crucial when looking at blood test results with your doctor.
The Quality Factor: Why Not All Creatine Is Created Equal
Now that we've discussed the compound itself, we have to talk about the most critical factor for your health: purity.
The supplement market is flooded with countless brands. Unfortunately, some companies may source their raw materials from unverified or untested laboratories overseas, with little transparency or quality control. In these cases, you may not know if you're getting pure creatine or a product containing industrial byproducts and other contaminants.
This is precisely why we created Clean Creatine. We made the decision to build our product on a foundation of purity and trust.
That's why we chose to use one, and only one, ingredient source: Creapure®, one of the most highly studied and purest forms of creatine in the world. Clean Creatine is proudly manufactured and packed in the United States under stringent quality control standards. By using only Creapure®, we ensure you are getting a product that meets a high standard for purity and quality.
Long-Term Safety and Dosing Considerations
Creatine is one of the most researched supplements on the planet. This extensive research gives us a clearer picture of its use over time, and long-term studies have not shown adverse effects in healthy individuals.
When it comes to dosing, it's always best to consult with your doctor to determine what's right for your individual needs. A commonly referenced daily dose is 5 grams for an average-sized person. Some larger individuals may use a higher dose to support their needs.
The only consistently reported side effect from creatine supplementation is the potential for minor gastrointestinal discomfort. To help avoid this, many people choose to take their creatine with a meal and stay well-hydrated throughout the day.
The Verdict: An Extensively Studied Supplement
After looking at the science, the picture becomes clearer. Creatine is:
A natural compound found in the body and in food.
Not a steroid.
The subject of extensive scientific research.
Most effective when you choose a product from a trusted brand committed to purity.
You were right to ask questions. We hope this information helps you feel more knowledgeable on the topic.
Ready to move forward with a brand that prioritizes quality? Experience the peace of mind that comes from the uncompromising quality of Clean Creatine.
Comments